Security & Compliance

Audit-ready. Always.

PureLIMS is built from the ground up for regulated environments — with immutable audit trails, e-signatures, RBAC, and compliance frameworks embedded into every workflow.

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Compliance frameworks, built in

Activate the regulatory frameworks your lab needs. Each framework adds the appropriate controls, audit points, and documentation requirements.

ISO/IEC 17025
Lab accreditation
21 CFR Part 11
Electronic records
CLIA
Clinical labs
GLP/GMP
Good practices
HIPAA
Patient data
EU Annex 11
Computerized systems
ISO 27001
Information security
SOC 2
Service controls

21 CFR Part 11 Audit Trails

Computer-generated, timestamped, immutable audit logs at every critical control point. Every record creation, modification, and deletion is captured with user identity, timestamp, reason, and before/after values.

  • Computer-generated, timestamped audit entries
  • Immutable log storage with integrity verification
  • Before/after value capture on every change
  • Reason-for-change prompts at critical control points
  • Configurable audit scope per workflow and record type
  • Export-ready for FDA and ISO inspection
21 CFR Part 11 Audit Trails
PureLIMS Module
1
Computer-generated, timestamped audit entries
2
Immutable log storage with integrity verification
3
Before/after value capture on every change
4
Reason-for-change prompts at critical control points

Role-Based Access Control

Fine-grained RBAC with group-based security, record-level constraints, and LDAP/SSO integration. Users see only what their role permits — down to the individual field level.

  • Group-based security with inherited permissions
  • Record-level access constraints
  • Field-level visibility and edit controls
  • LDAP and SSO integration for enterprise auth
  • Multi-factor authentication for sensitive operations
  • Session management with configurable timeout
Role-Based Access Control
PureLIMS Module
1
Group-based security with inherited permissions
2
Record-level access constraints
3
Field-level visibility and edit controls
4
LDAP and SSO integration for enterprise auth

Electronic Signatures

E-signatures capture identity, timestamp, meaning, and record linkage at every sign-off point. Compliant with 21 CFR Part 11, EU Annex 11, and GxP requirements.

  • Identity verification with password re-entry
  • Meaning capture (approved, reviewed, rejected)
  • Timestamp and record linkage on every signature
  • Configurable signature requirements per workflow step
  • Signature delegation with audit trail
  • Batch signature support for high-volume review
Electronic Signatures
PureLIMS Module
1
Identity verification with password re-entry
2
Meaning capture (approved, reviewed, rejected)
3
Timestamp and record linkage on every signature
4
Configurable signature requirements per workflow step

Data Security & Encryption

AES-256 encryption at rest, TLS 1.3 in transit, tenant isolation, and continuous security monitoring. Your data stays secure whether deployed on-cloud or on-premise.

  • AES-256 encryption for data at rest
  • TLS 1.3 for all data in transit
  • Tenant-isolated database architecture
  • Continuous vulnerability scanning
  • Penetration testing on every major release
  • SOC 2 Type II and ISO 27001 alignment
Data Security & Encryption
PureLIMS Module
1
AES-256 encryption for data at rest
2
TLS 1.3 for all data in transit
3
Tenant-isolated database architecture
4
Continuous vulnerability scanning

Change Control & Approval

Managed approval workflows for changes to static data, configurations, and critical system settings. Every change is proposed, reviewed, approved, and logged before taking effect.

  • Change request workflow with approval routing
  • Multi-level approval chains for critical changes
  • Automated notifications for pending approvals
  • Change history with full before/after comparison
  • Rollback capability for configuration changes
  • Change freeze periods for audit preparation
Change Control & Approval
PureLIMS Module
1
Change request workflow with approval routing
2
Multi-level approval chains for critical changes
3
Automated notifications for pending approvals
4
Change history with full before/after comparison

Compliance Framework Support

Built-in support for ISO 17025, 21 CFR Part 11, CLIA, GLP/GMP, HIPAA, and EU Annex 11. Configurable compliance profiles let you activate the frameworks relevant to your lab.

  • ISO/IEC 17025 accreditation workflows
  • 21 CFR Part 11 electronic records compliance
  • CLIA proficiency testing integration
  • GLP/GMP documentation and training tracking
  • HIPAA-aware access controls for clinical data
  • EU Annex 11 computerized system validation support
Compliance Framework Support
PureLIMS Module
1
ISO/IEC 17025 accreditation workflows
2
21 CFR Part 11 electronic records compliance
3
CLIA proficiency testing integration
4
GLP/GMP documentation and training tracking

See how PureLIMS handles compliance

Walk through audit trails, e-signatures, and the compliance cockpit with one of our specialists.

Schedule a Demo